Infectious mouse-adapted ME7 scrapie prion fibril purified from terminally-infected mouse brains
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8a00
Q-score: 0.633
Manka SW, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF
Nat Chem Biol (2023) 19 pp. 607-613 [ DOI: doi:10.1038/s41589-022-01229-7 Pubmed: 36646960 ]
- Major prion protein (15 kDa, Protein from house mouse)
- Amyloid fibril of prion protein (Complex from Mus musculus)
Infectious mouse-adapted RML scrapie prion fibrils purified from terminally-infected mouse brains
Manka SW, Zhang W, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF
Nat Commun (2022) 13 [ DOI: 10.1038/s41467-022-30457-7 Pubmed: 35831275 ]
Image sets:
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Resolution: 2.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 7qig
Q-score: 0.632
Manka SW, Zhang W, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF
Nat Commun (2022) 13 pp. 4004-4004 [ DOI: doi:10.1038/s41467-022-30457-7 Pubmed: 35831275 ]
Tomographic reconstruction of ex vivo mammalian prions
Terry C, Wenborn A, Gros N, Sells J, Joiner S, Hosszu LL, Tattum MH, Panico S, Clare DK, Collinge J, Saibil HR, Wadsworth JD
Open Biol (2016) 6 [ DOI: doi:10.1098/rsob.160035 Pubmed: 27249641 ]
Nicoll AJ, Panico S, Freir DB, Wright D, Terry C, Risse E, Herron CE, O'Malley T, Wadsworth JD, Farrow MA, Walsh DM, Saibil HR, Collinge J
Nat Commun (2013) 4 pp. 2416-2416 [ Pubmed: 24022506 DOI: doi:10.1038/ncomms3416 ]
- Amyloid-beta (1-42) (Protein from Homo sapiens)
- Amyloid-beta (1-42) nanotube (500 kDa, Sample)
Saibil HR, Seybert A, Habermann A, Winkler J, Eltsov M, Perkovic M, Castano-Diez D, Scheffer MP, Haselmann U, Chlanda P, Lindquist S, Tyedmers J, Frangakis AS
PNAS (2012) 109 pp. 14906-14911 [ Pubmed: 22927413 DOI: doi:10.1073/pnas.1211976109 ]
Saibil HR, Seybert A, Habermann A, Winkler J, Eltsov M, Perkovic M, Castano-Diez D, Scheffer MP, Haselmann U, Chlanda P, Lindquist S, Tyedmers J, Frangakis AS
PNAS (2012) 109 pp. 14906-14911 [ Pubmed: 22927413 DOI: doi:10.1073/pnas.1211976109 ]
Motor mechanism for protein threading through Hsp104
Wendler P, Shorter J, Snead D, Plisson C, Clare DK, Lindquist S, Saibil HR
Mol Cell (2009) 34 pp. 81-92 [ DOI: doi:10.1016/j.molcel.2009.02.026 Pubmed: 19362537 ]
- S. cerevisiae hsp104 n728a atp, asymmetric reconstruction (612 kDa, Sample)
- Hsp104 n728a (102 kDa, Protein from Saccharomyces cerevisiae)
Motor mechanism for protein threading through Hsp104
Wendler P, Shorter J, Snead D, Plisson C, Clare DK, Lindquist S, Saibil HR
Mol Cell (2009) 34 pp. 81-92 [ DOI: doi:10.1016/j.molcel.2009.02.026 Pubmed: 19362537 ]
- S. cerevisiae hsp104 n728a adp (612 kDa, Sample)
- Hsp104 n728a (102 kDa, Protein from Saccharomyces cerevisiae)
Motor mechanism for protein threading through Hsp104
Wendler P, Shorter J, Snead D, Plisson C, Clare DK, Lindquist S, Saibil HR
Mol Cell (2009) 34 pp. 81-92 [ DOI: doi:10.1016/j.molcel.2009.02.026 Pubmed: 19362537 ]
- S. cerevisiae hsp104 n728a atp (612 kDa, Sample)
- Hsp104 n728a (102 kDa, Protein from Saccharomyces cerevisiae)